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By Friðjónsson, Jón

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Number of Nuclei . . . . . . . . . . . . . Nucleoli . . . . . . . . . . . . . . . . . Mitoses . . . . . . . . . . . . . . . . . 3 Cellular Features: Cytoplasm . . . . . . . Relative Amount . . . . . . . . . . . . . Quality and Contents . . . . . . . . . . . Shape and Definition . . . . . . . . . . . 5 Criteria of Malignancy . . . . . . . . . . 6 Cytology Report. . . . . . . . . . .

Myxoid and Mucinous Background. . . . . Lymphoid Background. . . . . . . . . . . Other Background Features . . . . . . . . 5 Cell Arrangement . . . . . . . . . . . . Clusters. . . . . . . . . . . . . . . . . Sheets . . . . . . . . . . . . . . . . . . Single Cells. . . . . . . . . . . . . . . . Papillary Arrangement. . . . . . . . . . . Other Features. . . . . . . . . . . . . . 7 Cellular Features: the Nucleus .

Diff Quik is usually used for rapid staining and the assessment of material adequacy, whilst May Grünwald Giemsa MGG is used for traditional laboratory staining in making a final diagnosis. The advantages of the Romanowsky staining are in a good definition of the cell outline and cytoplasmic contents. Nuclear detail may also be seen, although it is more difficult to appreciate than in Pap staining (Figs. 20). The preference for either Romanowsky or Pap stains is subjective and largely depends on local practices and an individual’s training.

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